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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53BP1
All Species:
20
Human Site:
S25
Identified Species:
73.33
UniProt:
Q12888
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12888
NP_001135451.1
1972
213574
S25
P
C
L
I
I
E
D
S
Q
P
E
S
Q
V
L
Chimpanzee
Pan troglodytes
XP_001158270
1972
213535
S25
P
C
L
I
I
E
D
S
Q
P
E
S
Q
V
L
Rhesus Macaque
Macaca mulatta
XP_001107220
1972
213653
S25
P
C
L
I
I
E
D
S
Q
P
E
S
Q
V
L
Dog
Lupus familis
XP_849774
1976
214088
S30
P
C
L
I
I
E
D
S
Q
P
E
S
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082071
2104
231430
S25
P
C
L
I
V
E
D
S
Q
P
E
S
G
V
A
Zebra Danio
Brachydanio rerio
NP_001073639
1709
184731
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798355
2169
238737
S32
P
C
F
I
V
L
D
S
Q
A
E
G
T
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.2
89.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.9
34.4
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
99.5
98.2
93.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
51.3
N.A.
N.A.
N.A.
N.A.
37.6
P-Site Identity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
0
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
29
% A
% Cys:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
72
0
0
0
0
86
0
0
15
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
86
58
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
72
0
0
15
0
0
0
0
0
0
0
0
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
86
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
86
0
0
0
58
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
86
0
0
0
72
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
29
0
0
0
0
0
0
0
0
72
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _